October 14, 2009
I used to pipette 4M NaCl stock solution into my lunchtime soup when I was a post-doc.
October 12, 2009
If I am exiting a public doorway in front of you, and I hold the door briefly as I exit so you can then hold it for yourself without it striking you, don’t stop in the doorway while I’m holding it and use both hands to button your coat. I’m not your motherfucking valet, cockwad.
October 11, 2009
October 11, 2009
Let’s beat those motherfucking minnesotan douchebags!!!!!!!!!!!!!!!
Biochem Belle posted something interesting yesterday concerning her own training history as a grad student and post-doc and how it will position her for securing a tenure-track faculty position in the biomedical sciences:
When I made the decision to pursue a career in science, I was almost done with my BS and jumped straight into grad school. I didn’t take/have much time to explore areas outside of chemistry/biochemistry. I gravitated to biochem, but as a grad student, I was fascinated by more heavily bio/biomed-related research. Bear encouraged his grad students to keep up with what was going on in the literature outside our area of interests. I took that to heart. And I became intrigued by two fields that were quite far removed, in both content and techniques, from my graduate work.
Ultimately I chose one of those fields–immunology–for my postdoc work. Part of my reasoning was that immunology is constantly changing and evolving. There is really no shortage of questions and problems to work on. There is certainly a place in immunology for biochemistry and for tools emerging from chemical biology labs, which are not being widely used. I wanted the change work on something that was really important, to work in a field where a novel discovery has the potential to change medicine. And, for reasons that I can’t even explain to myself, it just felt right. Maybe that’s a poor reason to choose a new field, but it was one of mine, nonetheless.
Of course, that decision has brought a lot of things with it–like learning (obviously) immunology and, perhaps not so obviously, (re)learning cell signaling and physiology. I also realize that this choice all but guarantees taking a second postdoc before I start searching for my ‘dream job’. Even then, it could very well count against me with some search committee/study section members that I switched fields. No one is guaranteed success in science, but sometimes I’m afraid that I might have made it much more difficult for myself. [emphasis added]
She’s got this completely backwards! Having received training in multiple fields that one can then integrate to make oneself uniquely qualified to pursue an exciting creative research program as a new PI is exactly what search committees are looking for. Tenure-track faculty applicants who have always been working in the same field throughout their graduate and post-doctoral training are *less* attractive.
It is important to recognize that the biomedical sciences are currently at an inflection point. Over the last four decades, huge advances in our understanding of biology have arisen out of very fundamental conceptual and methodological developments in areas like biochemistry, molecular biology, and genetics. And these developments–because they were so fundamental–were also extremely general: DNA is DNA, and cloning and sequencing and knocking-out genes is exactly the same regardless of what gene is being attacked, what sort of protein it encodes, and what biological processes it participates in.
Using these very powerful general approaches, we have now achieved a nearly complete picture of all the molecular and cellular players that work together within organisms to generate biological function. What we still know very little about, however, is how these players work together to generate cellular, tissue, organ system, and organismic function. This is physiology!
Individuals who have substantial training in the methodological and conceptual foundations of fundamental areas like biochemistry, molecular biology, biophysics, and genetics, but who also have substantial training in the application of those tools in complex physiological contexts involving cells, tissues, organ systems, and entire organisms are the people who are going to lead the biomedical sciences through this inflection point. And these are the people who are most attractive to tenure-track faculty search committees (at least ones that are not dominated by close-minded fuckups).
October 10, 2009
October 9, 2009
What’s the over-under on the number of sick-fuck right-wing wackaloon shitbag whiny-ass titty-babies who wail that it was really George W. Bush who totes deserved the Nobel peace prize?
October 8, 2009
Wow this shit is totally fucking awesome, right?
Democrats are breathing a sigh of relief after a positive cost report on health care overhaul gave them a chance to rally around a Senate plan that significantly expands coverage while trimming the federal deficit. The Congressional Budget Office said Wednesday that the latest version of the Senate Finance Committee proposal would expand coverage to 94 percent of all eligible Americans at a 10-year cost of $829 billion.
The budget umpires added that the legislation would reduce federal deficits by $81 billion over a decade and could lead to continued reductions in federal red ink in the years beyond.
Estimated War-Related Costs, Iraq and Afghanistan
According to the Center for Defense Information, the estimated cost of the wars in Iraq and Afghanistan will reach $864 billion by the end of fiscal year 2009.
In billions of budgeted
Total Iraq $53.0 $75.9 $84.6 $101.9 $133.2 $526 $657 $1,631.6 Afghanistan 20.8 14.7 14.5 20.9 19.1 36.8 140 173 439.8 Enhanced security 13.0 8.0 3.7 2.1 0.8 0.4 28 5 61.0 Unable to allocate 5.5 5 5 15.5 Totals $33.8 $81.1 $94.1 $107.6 $121.8 $170.4 $700 $864 $2,172.8Source: “The Cost of Iraq, Afghanistan, and Other Global War on Terror Operations Since 9/11,” Amy Belasco, Congressional Research Service Report for Congress, RL33110, p. CRS-6); and Center for Defense Information, “Defense Budget Tutorial: So, You Think You Know the Cost of the Wars?” Web: www.cdi.org.
These motherfucking pathetic douchebags are “breathing a sigh of relief” that a mostly-useless bipartisaned-to-fucking-death health care bill is only gonna cost $829 billion over ten motherfucking years, when the wars of choice in Iraq and Afghanistan have already cost $2172 billion over eight years, and have cost $864 just in the motherfucking 2009 fiscal year (which just ended)? And all this fucking sick-fuck right-wing handwringing about how it’s too expensive to give health care to everyone, and niggers, spics, liberals, artists, non-muslim-hating jews, poor people, and other assorted non-Real Americans should be left to die in the motherfucking gutter because they don’t “deserve” health care, but Real Hard-Working Americans (i.e., white racist christian theocrat scumbags and white plutocrat greedfucks) do?
While Democrats breathe their sigh of relief and rally around their eviscerated piece-of-shit “health” (i.e., full bonuses for greedfuck health corp CEOs) plan, excuse me while I fucking puke.
October 7, 2009
October 2, 2009
How fucking pathetic is it that the Tampa Bay Rays’ mascot is not a motherfucking ray?